Joanne Esher Ryan of Wilmington, DE passed away peacefully Monday, September 17, 2018. She was 72 years young. Raised in Thornton, PA, she was the daughter of the late Dorothy (Didi) Esher and the late Joseph Esher and the sister to the late Jody Esher. She was the beloved wife of Ralph Butch (RB) Ryan and mother of Bobbi Reynolds and her husband Gary Reynolds, Carrie Gregori, and Adam Gregori and his wife Christine; Gammy of Casey, Colton, Morgan, Aiden, Kelly, Emily and Matt; and Great Gammy to Charlotte (Wylee); and sister to Judy Grady, Julie Smith and Jack Esher and his wife Sandy; and aunt of Amy Berlin, Bill Schnatz, John Esher, Jodi Esher, Justin Smith and Chase Smith.

She will always be remembered for her free spirit, beautiful smile, contagious laugh and amazing cocktails. A family service will be held on Thursday, September 20, 2018.

In lieu of flowers, memorial donations may be made to the Juvenile Diabetes Research Foundation,, 100 West 10th Street, Suite 1103, Wilmington, DE 19801.